- ANSES report (Referral No. 2025-AST-0038) validated December 5, 2025, recommends maximum nicotine limit for all combustible tobacco products in France.
- Report cites 22nd Century's VLN technology as the only commercially available production path for very-low-nicotine cigarettes.
- 22nd Century has FDA authorization for VLN product line (Dec 2019) and MRTP designation (Dec 2021).
- Company now offers non-GMO reduced-nicotine tobacco at commercial scale.
- European Commission launched call for evidence on May 18, 2026; legislative proposals expected before end of 2026.
- French health agency ANSES published a scientific assessment recommending a maximum nicotine limit for all combustible tobacco products in France, citing 22nd Century Group's VLN technology as the only commercially available production path for very-low-nicotine cigarettes. The company now offers non-GMO reduced-nicotine tobacco at commercial scale, removing a key implementation barrier.
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